Research use only — not for human consumption. Not evaluated by the MHRA or FDA.
Peptides
MT 1 10mg
10 mg · Lyophilised powder
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| Form | Lyophilised powder |
|---|---|
| Purity specification | ≥ 99% by HPLC (supplier specification) |
| Storage | −20°C lyophilised · 2–8°C once reconstituted |
Research Overview
What Melanotan 1 is
Melanotan 1 (MT-1), also known by the generic name afamelanotide, is a synthetic 13-residue analogue of alpha-melanocyte-stimulating hormone (α-MSH). It differs from the native hormone by two substitutions, norleucine at position 4 and D-phenylalanine at position 7, giving the designation [Nle4, D-Phe7]-α-MSH. These changes increase both its stability and its potency at the melanocortin-1 receptor relative to the parent hormone. Its molecular weight is approximately 1,647 Da.
Research background
MT-1 was developed in the 1980s at the University of Arizona by the groups of Victor Hruby and Mac Hadley as part of a systematic programme of α-MSH analogue design. It is a linear peptide, in contrast to the cyclic Melanotan 2, and shows greater selectivity for MC1R. It is a standard tool compound in melanocortin receptor pharmacology and in melanocyte and keratinocyte cell-culture research, and it has been characterised extensively through clinical development. Megalab supplies MT-1 as a research reagent only.
Specification
Each vial contains 10mg of Melanotan 1 as a lyophilised powder. Purity is verified by HPLC at ≥99% on every batch. Lot information appears in the batch record on this page where published, and a Certificate of Analysis is available on request.
Handling and storage
Store unopened vials at −20°C, protected from light; melanocortin analogues are light-sensitive and should be kept in amber or foil-wrapped containers once reconstituted. Bring to room temperature before opening. Reconstitute with bacteriostatic water added slowly down the vial wall and swirl gently. Store at 2–8°C after reconstitution and use within 30 days.
Supplied for laboratory research use only.
Reconstitution & storage
- Diluent
- Bacteriostatic water, added slowly down the inside wall of the vial; swirl, do not shake.
- Lyophilised
- Store at −20°C, away from light and moisture.
- Reconstituted
- Refrigerate at 2–8°C.
Frequently Asked Questions
What is the difference between Melanotan 1 and Melanotan 2?
MT-1 is a linear 13-residue analogue with relative selectivity for MC1R. MT-2 is a shorter cyclic heptapeptide that acts across several melanocortin receptor subtypes. Researchers select between them according to the receptor profile their protocol requires.
Is Melanotan 1 the same as afamelanotide?
Yes. Afamelanotide is the generic name for the same [Nle4, D-Phe7]-α-MSH sequence. This product is supplied as a research-grade reagent.
Is MT-1 light-sensitive?
Yes. Store lyophilised vials away from light, and keep reconstituted solution in an amber vial or wrapped in foil at 2–8°C.
