Research use only — not for human consumption. Not evaluated by the MHRA or FDA.
Peptides
GHK-Cu 50mg
50 mg · Lyophilised powder
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| Form | Lyophilised powder |
|---|---|
| Amount | 50 mg per vial |
| Purity specification | ≥ 99% by HPLC (supplier specification) |
| Storage | −20°C lyophilised · 2–8°C once reconstituted |
| Reconstitution | 5ml bacteriostatic water → 10,000 mcg/ml |
| CAS | 49557-75-7 / 89030-95-5 |
| Sequence | Gly‑ |
| Formula | C14H23CuN6O4 |
| Molecular weight | 402.9 g/mol |
| Synonyms | Copper Tripeptide-1; Glycyl-L-Histidyl-L-Lysine Cu(II) |
Research Overview
What GHK-Cu is
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (Gly-His-Lys). The peptide alone has a molecular weight of approximately 340 Da; complexed with copper it is approximately 403 Da. GHK was first isolated from human plasma by Loren Pickart in 1973, and its strong affinity for copper ions was characterised soon after. The reconstituted solution is distinctly blue, a visible marker of the copper complex.
Research background
GHK-Cu is among the most widely cited short peptides in the dermatological and wound-biology literature. Published work covers its effects on fibroblast gene expression in culture, collagen and glycosaminoglycan synthesis in tissue models, and its role as a copper carrier. It is also a common ingredient in cosmetic formulation research. Megalab supplies GHK-Cu as a laboratory reagent only.
Specification
Each vial contains 50mg of GHK-Cu as a lyophilised powder, a larger fill than most products in the range, reflecting the quantities typically used in formulation and cell-culture work. Purity is verified by HPLC at ≥99% on every batch. Lot details appear in the batch record on this page where published, and a Certificate of Analysis is available on request.
Handling and storage
Store unopened vials at −20°C, protected from light. Bring to room temperature before opening. Reconstitute with bacteriostatic water added slowly down the vial wall and swirl gently; the solution will turn blue as the complex dissolves. Store at 2–8°C after reconstitution and use within 30 days. Note that the 50mg fill means diluent volumes for typical working concentrations are larger than for 5mg or 10mg products; the peptide calculator handles this directly.
Supplied for laboratory research use only.
Reconstitution & storage
- Diluent
- Bacteriostatic water, added slowly down the inside wall of the vial; swirl, do not shake.
- 50mg + 5ml
- 10,000 mcg/ml · 1,000 mcg per 10 IU
- 50mg + 10ml
- 5,000 mcg/ml · 500 mcg per 10 IU
- Lyophilised
- Store at −20°C, away from light and moisture.
- Reconstituted
- Refrigerate at 2–8°C.
Frequently Asked Questions
Why is reconstituted GHK-Cu blue?
The colour comes from the copper(II) ion complexed to the tripeptide. A clear blue solution indicates the complex is intact; a colourless solution would suggest the copper has dissociated.
What is the difference between GHK and GHK-Cu?
GHK is the bare tripeptide Gly-His-Lys. GHK-Cu is the same peptide complexed with a copper(II) ion. This product is the copper complex.
Why is this vial 50mg rather than 5mg or 10mg?
GHK-Cu is commonly used in larger quantities in formulation and culture work than most research peptides, so a 50mg fill offers better value for those protocols.
