Research use only — not for human consumption. Not evaluated by the MHRA or FDA.
Peptides
TB-500 5mg
5 mg · Lyophilised powder
Order by 2pm for same-day dispatch. Free UK next-day tracked delivery.
| Form | Lyophilised powder |
|---|---|
| Amount | 5 mg per vial |
| Purity specification | ≥ 99% by HPLC (supplier specification) |
| Storage | −20°C lyophilised · 2–8°C once reconstituted |
| Reconstitution | 2ml bacteriostatic water → 2,500 mcg/ml |
| CAS | 77591-33-4 |
| Formula | C212H350N56O78S |
| Molecular weight | 4,963 g/mol |
| Synonyms | Thymosin Beta-4; Tβ4 synthetic analogue |
Research Overview
What TB-500 is
TB-500 is the synthetic form of thymosin beta-4 (Tβ4), a 43-residue peptide that is one of the most abundant intracellular peptides in mammalian cells. Its molecular weight is approximately 4,963 Da. Thymosin beta-4 was originally isolated from calf thymus in the 1980s and was later found to be present in nearly all cell types, where its principal known function is to bind monomeric G-actin and regulate the pool available for filament assembly. The actin-binding activity maps to a central motif with the sequence LKKTET.
Research background
Thymosin beta-4 has a substantial literature in cell biology and preclinical models. Published work covers actin dynamics, cell migration and angiogenesis in culture, and tissue models of cardiac, dermal and corneal repair in animals. It has also been examined in early clinical studies. Its combination with BPC-157 is a common request in research supply and is offered by Megalab as the Wolverine Stack. TB-500 is supplied as a research reagent only.
Specification
Each vial contains 5mg of TB-500 as a lyophilised powder. Purity is verified by HPLC at ≥99% on every batch. The batch record on this page shows the current lot where published, and a Certificate of Analysis is available on request.
Handling and storage
Store unopened vials at −20°C and protect from light. Allow to reach room temperature before opening. TB-500 is a larger peptide than most in the range; add bacteriostatic water slowly down the vial wall and allow the powder to hydrate before swirling gently. Do not shake. Store reconstituted solution at 2–8°C and use within 30 days.
Supplied for laboratory research use only.
Reconstitution & storage
- Diluent
- Bacteriostatic water, added slowly down the inside wall of the vial; swirl, do not shake.
- 5mg + 2ml
- 2,500 mcg/ml · 250 mcg per 10 IU
- 5mg + 1ml
- 5,000 mcg/ml · 500 mcg per 10 IU
- Lyophilised
- Store at −20°C, away from light and moisture.
- Reconstituted
- Refrigerate at 2–8°C.
Frequently Asked Questions
Is TB-500 the same as thymosin beta-4?
TB-500 is the name used in research supply for synthetic thymosin beta-4. This product is the 43-residue sequence.
What does thymosin beta-4 do in cells?
It binds monomeric actin and regulates the pool available for filament assembly, which is why it features prominently in research on cell migration and cytoskeletal dynamics.
Is TB-500 available with BPC-157?
Yes. The Wolverine Stack pairs one vial of TB-500 with one vial of BPC-157 at a reduced combined price.
